2-Chloro-4-picoline

  • CasNo:3678-62-4
  • purity:99%
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1.What is the 2-Chloro-4-picoline ?

2-Chloro-4-methylpyridine is used as a reagent in the synthesis of the mGLUR5 modulators imidazolyl-ethynyl-pyridines as potential antipsychotics. It is also used in the preparation of trifluoromethyl(pyrimidinyl)azetidinecarboxamides as potent, orally bioavailable TGR5 agonists.

4-methylpyridine-1-oxide
1003-67-4

4-methylpyridine-1-oxide

2-chloro-4-picoline
3678-62-4

2-chloro-4-picoline

4-picolylchloride hydrochloride
1822-51-1

4-picolylchloride hydrochloride

Conditions
Conditions Yield
With diisopropylamine; trichloromethyl chloroformate; In dichloromethane; at -40 - 20 ℃;
2-chloro-4-picoline
3678-62-4

2-chloro-4-picoline

(2-chloropyridin-4-yl)methanol
100704-10-7

(2-chloropyridin-4-yl)methanol

Conditions
Conditions Yield

2.What is the CAS number for 2-Chloro-4-picoline ?

The CAS number of 2-Chloro-4-picoline is 3678-62-4.

More information of 2-Chloro-4-picoline 3678-62-4 are:

CAS?Number

3678-62-4

Density

1.15 g/cm3

Melting Point

115°C

Boiling Point

195.3 °C at 760 mmHg

Flash Point

89.6 °C

Vapor Pressure

0.593mmHg at 25°C

Refractive Index

n20/D 1.529(lit.)

HS CODE

29349990

PSA

12.89000

LogP

2.04340

Pka

0.94±0.10(Predicted)

3.What are another words for 2-Chloro-4-picoline ?

Synonyms?for?2-Chloro-4-picoline 3678-62-4:2-chloro-4-methyl-pyridine;2-Chloro-4-methylpyridine;

4.What is the molecular formula of 2-Chloro-4-picoline?

The chemical formula of ?2-Chloro-4-picoline is?C6H6ClN which containing 6 Carbon atoms,6 Hydrogen atoms,1 Chlorine atoms and 1 Nitrogen atoms,and the molecular weight of??2-Chloro-4-picoline?is 127.573.

5.What is 2-Chloro-4-picoline (3678-62-4) used for?

2-Chloro-4-picoline, also known as 2-Chloro-4-methylpyridine, is a colorless to light yellow liquid that is a key intermediate in the synthesis of various pharmaceutical compounds. It is known for its reactivity in palladium-catalyzed cross-coupling reactions, which makes it a valuable building block in the development of new drugs.

InChI:InChI=1/C6H6ClN/c1-5-2-3-8-6(7)4-5/h2-4H,1H3

Relevant articles related to 2-Chloro-4-picoline:

Article

Source

Preparation method of non-transition metal-catalyzed 2-halogenated pyridine compound

-

Paragraph 0064-0066, (2018/10/11)

Preparation of an Arenylmethylzinc Reagent with Functional Groups by Chemoselective Cross-Coupling Reaction of Bis(iodoazincio)methane with Iodoarenes

Shimada, Yukako,Haraguchi, Ryosuke,Matsubara, Seijiro

, p. 2395 - 2398 (2015/10/19)

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