Details
Perfect Factory Offer Excellent quality 4-(2,5-Dioxopyrrolidin-1-yl)benzenesulfonamide 5470-06-4 with Safe Shipping
- Molecular Formula: C10H10N2O4S
- Molecular Weight: 254.266
- Vapor Pressure: 2.05E-14mmHg at 25°C
- Refractive Index: 1.64
- Boiling Point: 601.267 °C at 760 mmHg
- Flash Point: 317.435 °C
- PSA： 105.92000
- Density: 1.533 g/cm3
- LogP: 1.83350
4-(2,5-Dioxopyrrolidin-1-yl)benzenesulfonamide(Cas 5470-06-4) Usage
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General Description |
4-(2,5-Dioxopyrrolidin-1-yl)benzenesulfonamide is a chemical compound that is commonly used as a diuretic and antihypertensive medication. It works by inhibiting the enzyme carbonic anhydrase, which is involved in the production of bicarbonate ions in the kidneys. This leads to decreased reabsorption of sodium and water, resulting in increased urine production and reduced fluid retention. The compound is also being investigated for its potential anti-cancer properties, as it has been shown to inhibit the growth of tumor cells in some studies. Additionally, 4-(2,5-Dioxopyrrolidin-1-yl)benzenesulfonamide has been used in the treatment of glaucoma, epilepsy, and altitude sickness, among other conditions. |
InChI:InChI=1/C10H10N2O4S/c11-17(15,16)8-3-1-7(2-4-8)12-9(13)5-6-10(12)14/h1-4H,5-6H2,(H2,11,15,16)
5470-06-4 Relevant articles
Molecular design, synthesis and biological evaluation of cyclic imides bearing benzenesulfonamide fragment as potential COX-2 inhibitors. Part 2
Al-Suwaidan, Ibrahim A.,Alanazi, Amer M.,El-Azab, Adel S.,Al-Obaid, Abdulrahman M.,Eltahir, Kamal E.H.,Maarouf, Azza R.,Abu El-Enin, Mohamed A.,Abdel-Aziz, Alaa A.-M.
, p. 2601 - 2605 (2013/06/27)
A group of cyclic imides (1-10) was desi...
5470-06-4 Process route
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108-30-5
succinic acid anhydride
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63-74-1
sulfanilamide
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-
5470-06-4
N ,N -succinyl-sulfanilic acid amide
| Conditions | Yield |
|---|---|
|
With
pyridine;
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|
|
at 170 ℃;
|
|
|
With
acetic acid;
for 24h;
Reflux;
|
-
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40686-14-4
4-(2,5-dioxopyrrolidin-1-yl)benzenesulphonyl chloride
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-
5470-06-4
N ,N -succinyl-sulfanilic acid amide
| Conditions | Yield |
|---|---|
|
With
pyridine; water; acetone;
Reagens 4:Ammoniak;
|
5470-06-4 Upstream products
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108-30-5
succinic acid anhydride
-
63-74-1
sulfanilamide
-
40686-14-4
4-(2,5-dioxopyrrolidin-1-yl)benzenesulphonyl chloride
-
3563-14-2
4-{3-carboxy-propionylamino}-benzene-1-sulfonamide
5470-06-4 Downstream products
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3563-14-2
4-{3-carboxy-propionylamino}-benzene-1-sulfonamide
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