Details
2-Methyl-1-phenyl-2-propanol GMP Manufacturer Global Trade 100-86-7 with Fast Delivery
- Molecular Formula: C10H14O
- Molecular Weight: 150.221
- Appearance/Colour: Colorless and transparent liquid
- Vapor Pressure: 0.0888mmHg at 25°C
- Melting Point: 23-25 °C(lit.)
- Refractive Index: n20/D 1.514(lit.)
- Boiling Point: 215 °C at 760 mmHg
- PKA: 15.31±0.29(Predicted)
- Flash Point: 81.1 °C
- PSA： 20.23000
- Density: 0.982 g/cm3
- LogP: 2.00000
2-Methyl-1-phenyl-2-propanol(Cas 100-86-7) Usage
|
Preparation |
From acetone and benzyl magnesium chloride or benzyl magnesium bromide. |
|
Synthesis Reference(s) |
Tetrahedron Letters, 27, p. 3129, 1986 DOI: 10.1016/S0040-4039(00)84733-4 |
|
Flammability and Explosibility |
Notclassified |
|
Safety Profile |
Moderately toxic by ingestion. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. |
InChI:InChI=1/C10H14O/c1-10(2,11)8-9-6-4-3-5-7-9/h3-7,11H,8H2,1-2H3
100-86-7 Relevant articles
Reactivity of a Palladacyclic Complex: A Monodentate Carbonate Complex and the Remarkable Selectivity and Mechanism of a Neophyl Rearrangement
Behnia, Ava,Fard, Mahmood A.,Blacquiere, Johanna M.,Puddephatt, Richard J.
, p. 4759 - 4769 (2017)
The ligand N(CH2-2-C5H4N)2(CH2CH2CH2OH),...
Heterolytic cleavage of peroxide by a diferrous compound generates metal-based intermediates identical to those observed with reactions utilizing oxygen-atom-donor molecules
Rowe, Gerard T.,Rybak-Akimova, Elena V.,Caradonna, John P.
, p. 8303 - 8311 (2008)
Under cryogenic stoppedflow conditions, ...
-
Tiffeneau,Delange
, p. 575 (1903)
-
Cyclobutylcarbinyl p-Bromobenzenesulfonate Solvolysis. A Stady of Response to Solvent Ionizing Strength
Roberts, Donald D.
, p. 561 - 564 (1982)
-
Catalytic Replacement of Unactivated Alkane Carbon-Hydrogen Bonds with Carbon-X Bonds (X = Nitrogen, Oxygen, Chlorine, Bromine, or Iodine). Coupling of Intermolecular Hydrocarbon Activation by MnIIITPPX Complexes with Phase-Transfer Catalysis
Hill, Craig L.,Smegal, John A.,Henly, Timothy J.
, p. 3277 - 3281 (1983)
A simple system has been devised to faci...
Tuning the selectivity in the aerobic oxidation of cumene catalyzed by nitrogen-doped carbon nanotubes
Liao, Shixia,Chi, Yumei,Yu, Hao,Wang, Hongjuan,Peng, Feng
, p. 555 - 560 (2014)
In this study it is demonstrated that ca...
Use of Sacrificial Anodes in Electrochemical Functionalization of Organic Halides
Chaussard, Jacques,Folest, Jean-Claude,Nedelec, Jean-Yves,Perichon, Jacques,Sibille, Soline,Troupel, Michel
, p. 369 - 381 (1990)
This article reviews the new possibiliti...
Mechanistic Insights into Fe Catalyzed α-C?H Oxidations of Tertiary Amines
Legacy, Christopher J.,Hope, Taylor O.,Gagné, Yohann,Greenaway, Frederick T.,Frenette, Mathieu,Emmert, Marion H.
, p. 235 - 246 (2021)
We report detailed mechanistic investiga...
Model dialkyl peroxides of the fenton mechanistic probe 2-methyl-1-phenyl-2-propyl hydroperoxide (MPPH): Kinetic probes for dissociative electron transfer
Magri, David C.,Workentin, Mark S.
, p. 3418 - 3429 (2003)
Two dialkyl peroxides, devised as kineti...
-
Singh
, p. 714 (1971)
-
Visible-Light-Driven Palladium-Catalyzed Radical Alkylation of C?H Bonds with Unactivated Alkyl Bromides
Zhou, Wen-Jun,Cao, Guang-Mei,Shen, Guo,Zhu, Xing-Yong,Gui, Yong-Yuan,Ye, Jian-Heng,Sun, Liang,Liao, Li-Li,Li, Jing,Yu, Da-Gang
, p. 15683 - 15687 (2017)
Reported herein is a novel visible-light...
-
Frank,Foster
, p. 1019 (1954)
-
Hydrocarbon Functionalization by the (Iodosylbenzene)manganese(IV) Porphyrin Complexes from the (Tetraphenylporphinato)manganese(III)-Iodosylbenzene Catalytic Hydrocarbon Oxidation System. Mechanism and Reaction Chemistry
Smegal, John A.,Hill, Craig L.
, p. 3515 - 3521 (1983)
The two types of complexes isolated from...
Highly powerful and practical acylation of alcohols with acid anhydride catalyzed by Bi(OTf)3
Orita,Tanahashi,Kakuda,Otera
, p. 8926 - 8934 (2001)
Bi(OTf)3-catalyzed acylation of alcohols...
UN NOVEAU SYNTHON ORGANOSILICIE: LE BENZYLTRIMETHYLSILANE
Bennetau, Bernard,Dunogues, Jacques
, p. 4217 - 4218 (1983)
In the presence of tetrabutylammonium fl...
A polymer-supported diacetatobis(2-quinolylbenzimidazole)copper(II) complex as an efficient catalyst for oxidation of alcohols with tert-butyl hydroperoxide
Shilpa,Gayathri
, p. 53 - 62 (2013)
A polymer-supported diacetatobis(2-quino...
Generation of Anionic Intermediates by Intramolecular Nucleophilic Attack at Silicon
Hudrlik, Paul F.,Abdallah, Yousef M.,Hudrlik, Anne M.
, p. 6747 - 6750 (1992)
Benzyl and allyl anion equivalents can b...
Ultrafast Grignard addition reactions in the presence of water
Osztrovszky, Gyorgyi,Holm, Torkil,Madsen, Robert
, p. 3402 - 3404 (2010)
The addition of allylmagnesium bromide a...
Controlled stepwise release of fragrance alcohols from dendrimer-based 2-carbamoylbenzoates by neighbouring group participation
Frerot, Eric,Herbal, Karim,Herrmann, Andreas
, p. 967 - 971 (2003)
2-Carbamoylbenzoates which are chemicall...
Preparation of Samarium(II) Triflate and It Mediated Grignard-type Reaction. In Situ Formation and Reaction of New Organosamarium Reagents
Fukuzawa, Shin-ichi,Tsuchimoto, Teruhisa,Kanai, Takeshi
, p. 1981 - 1984 (1994)
Samarium(II) triflate was readily prepar...
Samarium-mediated Barbier reaction of carbonyl compounds
Basu, Manas K.,Banik, Bimal K.
, p. 187 - 189 (2001)
Samarium metal in the presence of cataly...
Highly reactive and chemoselective cleavage of allyl esters using an air- and moisture-stable [CpRu(IV)(π-C3H5)(2-quinolinecarboxylato)]PF6 catalyst
Tanaka, Shinji,Saburi, Hajime,Murase, Takanori,Ishibashi, Yoshitaka,Kitamura, Masato
, p. 295 - 298 (2007)
A new catalytic process for allyl ester ...
REACTIVITE DE LA LIAISON δ ACTINIDE-CARBONE : LE TRIS(BISTRIMETHYLSILYLAMIDO)METHYLURANIUM, UN AGENT METHYLANT NUCLEOPHILE A HAUTE SELECTIVITE
Dormond, A.,Aaliti, A.,Moise,, C.
, p. 1497 - 1498 (1986)
The title compound 1 reacts with carbony...
[CpRu(IV)(π-C3H5)(2-quinolinecarboxylato)]PF 6 complex: A robust catalyst for the cleavage and formation of allyl ethers
Tanaka, Shinji,Saburi, Hajime,Kitamura, Masato
, p. 375 - 378 (2006)
A facile and efficient method for the qu...
Tuning the Diiron Core Geometry in Carboxylate-Bridged Macrocyclic Model Complexes Affects Their Redox Properties and Supports Oxidation Chemistry
Wang, Fang,Becker, Sabine,Minier, Mikael A.,Loas, Andrei,Jackson, Megan N.,Lippard, Stephen J.
, p. 11050 - 11058 (2017)
We introduce a novel platform to mimic t...
The chemistry of alkylstrontium halide analogues, Part 2: Barbier-type dialkylation of esters with alkyl halides
Miyoshi, Norikazu,Matsuo, Tsuyoshi,Wada, Makoto
, p. 4253 - 4255 (2005)
The chemistry of an alkylstrontium halid...
An asymmetric Salamo-based Zn complex supported on Fe3O4MNPs: a novel heterogeneous nanocatalyst for the silyl protection and deprotection of alcohols under mild conditions
Yao, Hongyan,Wang, Yongsheng,Razi, Maryam Kargar
, p. 12614 - 12625 (2021/04/14)
In this study, a magnetic asymmetric Sal...
Sulfonium ion-promoted traceless Schmidt reaction of alkyl azides
Ardiansah, Bayu,Kakiuchi, Kiyomi,Morimoto, Tsumoru,Tanimoto, Hiroki,Tomohiro, Takenori
supporting information, p. 8738 - 8741 (2021/09/08)
Schmidt reaction by sulfonium ions is de...
DECOMPOSITION OF ORGANIC PEROXIDES AND HYDROGEN PEROXIDE BY THE IRON THIOLATES AND RELATED COMPLEXES
-
Paragraph 0730; 0733; 0786-0792, (2020/07/04)
Disclosed herein is a method of reducing...
100-86-7 Process route
-
-
538-93-2
1-phenyl-2-methylpropane
-
-
100-86-7
2-Methyl-1-phenyl-2-propanol
-
-
611-70-1
phenyl isopropyl ketone
| Conditions | Yield |
|---|---|
|
With
3,3-dimethyldioxirane;
In
acetone;
for 72h;
Ambient temperature;
|
4.0 % Chromat.
15.6 % Chromat. |
-
-
931-88-4,931-87-3,25267-51-0
cis-Cyclooctene
-
-
1944-83-8
2-methyl-1-phenyl-2-propylhydroperoxide
-
-
286-62-4
Cyclooctene oxide
-
-
100-86-7
2-Methyl-1-phenyl-2-propanol
-
-
100-52-7
benzaldehyde
-
-
103-29-7
1,1'-(1,2-ethanediyl)bisbenzene
| Conditions | Yield |
|---|---|
|
With
1H-imidazole; (1,2-dimethyl-4(1H)-pyridinone-3-olate)2MnCl;
In
acetonitrile;
at 4 ℃;
for 24h;
|
43 %Chromat.
41 %Chromat. 9 %Chromat. 5 %Chromat. |
100-86-7 Upstream products
-
1754-74-1
2-chloro-2-methyl-1-phenylpropane
-
100-44-7
benzyl chloride
-
67-64-1
acetone
-
917-64-6
methyl magnesium iodide
100-86-7 Downstream products
-
18010-63-4
nicotinic acid-(1,1-dimethyl-2-phenyl-ethylamide)
-
52117-13-2
N -(1,1-dimethyl-2-phenyl-ethyl)-formamide
-
538-93-2
1-phenyl-2-methylpropane
-
1985-96-2
1,2-diphenyl-2-methylpropane
Related Products
-
2,2',3,3',5,5',6,6'-octabromo-4-phenoxy-1,1'-biphenylCAS：83929-69-5
-
5-IODO-2-METHYLANILINECAS：83863-33-6
-
3-methylbut-2-enyl 2-methylisocrotonateCAS：83783-82-8