Details
Top quality factory supply 72544-16-2 1-Isobutyl-4-piperidone at low price
- Molecular Formula: C9H17NO
- Molecular Weight: 155.24
- Appearance/Colour: colorless to yellow liquid
- Melting Point: 28°C (estimate)
- Refractive Index: n20/D 1.456(lit.)
- Boiling Point: 233.3 °C at 760 mmHg
- PKA: 7.94±0.20(Predicted)
- Flash Point: 88.3 °C
- PSA： 20.31000
- Density: 0.94 g/cm3
- LogP: 1.24520
1-Isobutyl-4-piperidone(Cas 72544-16-2) Usage
|
General Description |
1-(2-Methylpropyl)-4-piperidone is a piperidone derivative. It can be synthesized by employing enamine derived from isobutyraldehyde and piperidone as a starting reagent. |
InChI:InChI=1/C9H17NO/c1-8(2)7-10-5-3-9(11)4-6-10/h8H,3-7H2,1-2H3
72544-16-2 Relevant articles
Design and synthesis of rho kinase inhibitors (III)
Iwakubo, Masayuki,Takami, Atsuya,Okada, Yuji,Kawata, Takehisa,Tagami, Yoshimichi,Sato, Motoko,Sugiyama, Terumi,Fukushima, Kayoko,Taya, Shinichiro,Amano, Mutsuki,Kaibuchi, Kozo,Iijima, Hiroshi
, p. 1022 - 1033 (2007/10/03)
The structure-activity relationship of R...
Synthesis of heteroarylpiperazines and heteroarylbipiperidines with a restricted side chain and their affinities for 5-HT1A receptor
Yoo, Kyung Ho,Choi, Hyun Sik,Kim, Dong Chan,Shin, Kye Jung,Kim, Dong Jin,Song, Yun Seon,Jin, Changbae
, p. 208 - 215 (2007/10/03)
Heteroarylpiperazine and heteroarylbipip...
Novel 1,4 substituted piperidine derivatives. Synthesis and correlation of antioxidant activity with structure and lipophilicity
Alexidis,Rekka,Demopoulos,Kourounakis
, p. 131 - 137 (2007/10/02)
A series of novel piperidine derivatives...
72544-16-2 Process route
-
-
41979-39-9
4-piperidone hydrochloride
-
-
72544-16-2
N-(2-methylpropyl)-4-piperidone
| Conditions | Yield |
|---|---|
|
With
potassium carbonate;
In
acetonitrile;
|
47.8%
|
-
-
3612-20-2
1-phenylmethyl-4-piperidone
-
-
72544-16-2
N-(2-methylpropyl)-4-piperidone
| Conditions | Yield |
|---|---|
|
Multi-step reaction
with
2
steps
1: 97 percent / H2
; aq. HCl / palladium hydroxide / ethanol / 24 h / 20 °C / 3102.89 Torr
2: 47.8 percent / K2
CO3
/ acetonitrile
With
hydrogenchloride; hydrogen; potassium carbonate;
palladium dihydroxide;
In
ethanol; acetonitrile;
|
72544-16-2 Upstream products
-
162258-31-3
dimethyl β,β'-isobutylaminodipropionate
-
88488-91-9
3,3'-isobutylimino-di-propionic acid diethyl ester
-
25012-73-1
1-isobutyl-4-oxo-piperidine-3-carboxylic acid methyl ester
-
41979-39-9
4-piperidone hydrochloride
Related Products
-
2,2',3,3',5,5',6,6'-octabromo-4-phenoxy-1,1'-biphenylCAS：83929-69-5
-
5-IODO-2-METHYLANILINECAS：83863-33-6
-
3-methylbut-2-enyl 2-methylisocrotonateCAS：83783-82-8